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How to determine, through clinical trials, whether the rotavirus vaccine is needed.
Release Date:
2020-10-29
author:
Every pig farm recognizes the importance of preventing porcine circovirus, but when exactly should preventive measures be taken, and how can we determine—through clinical observation and production data—whether to vaccinate against PCV? Meanwhile, most producers know very little about Mycoplasma hyopneumoniae. The damage caused by these two immunosuppressive diseases has never ceased and remains unresolved to this day. Below are the scenarios most farmers encounter when attempting to differentiate between porcine circovirus and mycoplasmosis: Should we interpret test results using PCR or ELISA techniques and then return to clinical practice? Pig farm owner: “I’m a small-scale operator—how could a family‑run operation afford such resources?” Or should we rely on postmortem pathological findings to distinguish between mycoplasmosis and porcine circovirus? Pig farm owner: “I’m not a veterinary expert.”
Every pig farm recognizes the importance of preventing porcine circovirus disease, but when exactly should preventive measures be taken, and how can we determine—through clinical observation and production data—whether to administer a PCV2 vaccine? Meanwhile, most producers know very little about Mycoplasma hyopneumoniae. The damage caused by these two immunosuppressive diseases has never ceased and remains unresolved to this day. The following scenarios reflect the typical challenges that many farmers face when differentiating between PCV2 and M. hyopneumoniae in diagnostic practice.
Understanding test reports using PCR and ELISA techniques—back to the bedside?
Pig farm: I’m a small-scale farmer—how could a family-run pig operation possibly meet those conditions?
Distinguish Mycoplasma rings by dissecting pathological changes.
Pig farm: I’m not a veterinary expert—when it comes to lung lesions, I can’t tell them apart at all!
Can these two diseases be diagnosed using “rapid test cards” sold on the market?
Pig farm: Some results are reliable, others aren’t—I’m starting to get confused myself. (In fact, the sensitivity and quantification of colloidal gold assays simply can’t be compared with those of ELISA.)
Can these two conditions be diagnosed based on clinical symptoms and findings?
Pig farm: As soon as a pig shows any sign of trouble, it’s all about bristling fur, emaciation, lethargy, respiratory issues—coughing and fever—leaving everyone utterly baffled!
In light of the above, we have compiled a checklist that draws on years of clinical experience and laboratory data. By grounding our approach in clinical practice, we can consistently identify evidence and clues to inform our decision-making.

If, after ruling out all other potential causes, the issues listed above remain unresolved, it is imperative to administer both the porcine circovirus and mycoplasma vaccines. When selecting a vaccine for porcine circovirus and mycoplasma, the HuiZhong Bio bivalent inactivated vaccine—targeting porcine circovirus type 2 and Mycoplasma hyopneumoniae—is the clear choice. This product boasts fully independent intellectual property rights and was the first to complete its R&D. Its proprietary water-based adjuvant, combined with advanced vaccine‑production technology, ensures superior quality, effectively mitigating risks such as adjuvant–antigen incompatibility and poor stability and uniformity that can arise when using separate monovalent vaccines. With a single injection providing dual protection, its long‑acting aqueous adjuvant is easy to draw and administer, causes minimal irritation, sustains circovirus antibody levels for over 150 days, and delivers mycoplasma protection that outperforms products from imported manufacturers.
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Huizhong Biotech
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Luoyang Huizhong Biotech Co., Ltd. is a private high-tech enterprise located in Luoyang City Luolong High-tech Industrial Development Zone. Based on the successful operation of Huizhong Veterinary Medicine for 20 years, the company adhere to high starting point and high standard new veterinary vaccines research and development, production, and promotion
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